Millions of people across the globe have received a COVID-19 vaccine. However, there are still numerous questions related to the effectiveness of these vaccines. One common question is whether there is a relationship between side effects observed after vaccination and subsequent immunity.
If you have not had any side effects after a COVID-19 vaccine, are you still protected? Image credit: Mayank Makhija/NurPhoto via Getty Images
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There are currently 21 COVID-19 vaccines authorized for use across the globe. In the United Kingdom, over 36,500,000 people have been fully vaccinated against COVID-19 to date. In the United States, more than 162,100,000 people are now fully vaccinated.
Worldwide, over 13% of the population have been fully vaccinated against COVID-19, according to the data compiled by Google.
Real-world vaccine safety monitoring continues for all vaccines, as the Centers for Disease Control and Prevention (CDC)Trusted Source state. Health authorities worldwide continue to encourage those who receive a COVID-19 vaccine to report any side effects to a healthcare professional.
Millions of vaccinated people have experienced side effects, including swelling, redness, and pain at the injection site. Fever, headache, tiredness, muscle pain, chills, and nausea are also commonly reportedTrusted Source.
As is the case with any vaccine, however, not everyone will react in the same way. Many people have not reported or experienced side effects after their vaccination. Does this mean that they are not protected against SARS-CoV-2?
‘No direct correlation between side effects and protection’
In an interview with Medical News Today, William Schaffner, M.D., professor of infectious diseases at Vanderbilt University Medical Center in Nashville, TN, spoke about the relationship between side effects and immunity to SARS-CoV-2, the virus that causes COVID-19.
He stated that neither the presence nor the absence of side effects indicates immunity. “There is no direct correlation between side effects and protection,” said Prof. Schaffner.
Data from the trials of the two-dose mRNA COVID-19 vaccines — Pfizer-BioNTech and Moderna — indicate that these are over 90%Trusted Source effective. Under 10% of those fully vaccinated may have partial to no protection.
Because of the way in which vaccines work — by prompting the body to build up immunity against the target pathogen — individuals with compromised immune systems may not be able to build up complete or even partial immunity to SARS-CoV-2.
According to Prof. Schaffner, some medications, such as immunosuppressants and some drugs used in cancer treatments, may also negatively impact the effectiveness of COVID-19 vaccines.
Source: Medical News Today